In NZ, Pepinos are grown in pots with three long bamboo stakes. The plant is cut off low to the ground and when it multi-trunks after being cut, the vines are trained up the stakes.
New Pepino plants require the centre to be pruned out and doing this encourages an open bush allowing greater light penetration and air movement.
A wire trellis in the form of a pyramid is needed to support the plant, keeping it upright especially when in fruit.
It is very susceptible to fruit fly, you either have to net or bait so design your trellis accordingly.